Search results for " coeliac disease"

showing 10 items of 14 documents

Vaccination Status and Attitudes towards Vaccines in a Cohort of Patients with Celiac Disease.

2022

(1) Background: The identification of vaccination status and attitudes towards vaccines among celiac disease (CD) patients is of great importance, but it has not yet been investigated. The aim of this study was to investigate coverage against vaccine-preventable diseases (VPDs), attitudes towards vaccinations, and its determinants among CD patients. (2) Methods: An anonymous web-based validated questionnaire was sent to a mailing list of CD adult patients. Patients were asked to self-report their previous vaccinations and attitudes towards vaccinations, which were defined as positive, negative, and partially positive/negative. The influencing factors towards vaccinations were investigated, …

celiac disease coeliac disease hyposplenism vaccine hesitancy vaccinesSettore BIO/13 - Biologia Applicatahyposplenismvaccine hesitancyvaccinesvaccines; vaccine hesitancy; celiac disease; coeliac disease; hyposplenismcoeliac diseaseceliac diseaseVaccines
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Low incidence but poor prognosis of complicated coeliac disease: A retrospective multicentre study.

2013

Abstract Background Coeliac disease is a chronic enteropathy characterized by an increased mortality caused by its complications, mainly refractory coeliac disease, small bowel carcinoma and abdominal lymphoma. Aim of the study was to study the epidemiology of complications in patients with coeliac disease. Methods Retrospective multicenter case–control study based on collection of clinical and laboratory data. The incidence of complicated coeliac disease was studied among coeliac patients directly diagnosed in four Italian centres. Patients referred to these centres after a diagnosis of coeliac disease and/or complicated coeliac disease in other hospitals were therefore excluded. Results B…

AdultMalePediatricsmedicine.medical_specialtyPoor prognosisLymphoma B-CellSettore MED/09 - Medicina InternaComplicationsCELIAC DISEASEcomplicated coeliac diseaseKaplan-Meier EstimateGastroenterologyCoeliac diseaseNOCohort StudiesEnteropathy-Associated T-Cell LymphomaRefractoryCELIAC DISEASE; ComplicationsInternal medicineEpidemiologyIntestinal NeoplasmsIntestine SmallmedicinePrevalenceHumansAgedRetrospective StudiesHepatologybusiness.industryIncidence (epidemiology)IncidenceCarcinomaGastroenterologyCurve analysisnutritional and metabolic diseasesMiddle Agedmedicine.diseasePrognosisdigestive system diseasesLymphomaItalyAbdominal NeoplasmsCase-Control StudiesCohortFemalebusiness
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A multicentre case control study on complicated coeliac disease: two different patterns of natural history, two different prognoses

2014

Background: Coeliac disease is a common enteropathy characterized by an increased mortality mainly due to its complications. The natural history of complicated coeliac disease is characterised by two different types of course: patients with a new diagnosis of coeliac disease that do not improve despite a strict gluten-free diet (type A cases) and previously diagnosed coeliac patients that initially improved on a gluten-free diet but then relapsed despite a strict diet (type B cases). Our aim was to study the prognosis and survival of A and B cases. Methods: Clinical and laboratory data from coeliac patients who later developed complications (A and B cases) and sex- and age-matched coeliac p…

MaleComplicationsSettore MED/09 - Medicina InternaLymphomaSmallGastroenterologyCoeliac diseaseEnteropathy-Associated T-Cell LymphomaIntestine SmallMedicineCeliac diseaseEnteropathyTreatment FailureINTESTINAL T-CELL LYMPHOMAGastroenterologyGLUTEN FREE DIETGeneral Medicinecomplicated coeliac disease; natural history; prognosis;IleitisMiddle AgedPrognosisEnteritisIntestineNatural historyAdult; Aged; Carcinoma; Case-Control Studies; Celiac Disease; Collagenous Sprue; Disease Progression; Enteritis; Enteropathy-Associated T-Cell Lymphoma; Female; Humans; Ileitis; Intestinal Neoplasms; Intestine Small; Jejunal Diseases; Lymphoma B-Cell; Male; Middle Aged; Prognosis; Treatment Failure; Diet Gluten-Freenatural historyGluten-free dietDisease ProgressionEnteropathy-associated T-cell lymphomaFemaleprognosiResearch ArticleCollagenous SprueAdultmedicine.medical_specialtyLymphoma B-CellGlutensSettore MED/12 - GASTROENTEROLOGIAcomplicated coeliac diseasecomplications/drug therapy/mortality Myocytes; celiac diseaseNODiet Gluten-FreeInternal medicineIntestinal NeoplasmsHumanscomplications/drug therapy/mortalitySurvival rateCELIAC DISEASE; Complications; INTESTINAL T-CELL LYMPHOMA; prognosis; GLUTEN FREE DIETAgedcomplications/drug therapy/mortality; Myocytes; celiac diseaseMyocytesbusiness.industryCarcinomaB-CellCase-control studynutritional and metabolic diseasesJejunal DiseasesHepatologymedicine.diseasedigestive system diseasesDietEATLCase-Control StudiesGluten-FreeGluten freebusinessComplicationcoeliac disease
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Production of Anti-Endomysial Antibodies in Cultured Duodenal Mucosa: Usefulness in Coeliac Disease Diagnosis

2002

Although anti-endomysial antibodies (EmA) have been found in the supernatants of cultured intestinal mucosa from patients with coeliac disease (CD), in no study has the clinical reliability of this new diagnostic tool been investigated. Our aims were to evaluate the clinical usefulness of the in vitro production of EmA in CD diagnosis in consecutive patients with suspected CD, and to evaluate the reliability of the in vitro challenge in CD patients on a gluten-free diet (GFD).For the former aim, consecutive patients who were due to undergo intestinal biopsy for suspected diagnosis of CD were enrolled: according to the final diagnosis, these patients were divided into two groups: Group 1 com…

AdultMaleanti-endomysial antibodiemedicine.medical_specialtySettore MED/09 - Medicina InternaAdolescentDuodenumIn Vitro TechniquesSensitivity and SpecificityGastroenterologyGliadinCoeliac diseaseIntestinal mucosaImmunopathologyInternal medicineSuspected diagnosisHumansMedicineChildCells CulturedAgedbiologybusiness.industryGastroenterologyInfantReproducibility of ResultsMiddle Agedcultured duodenal mucosa: coeliac disease diagnosismedicine.diseaseAntibodies Anti-IdiotypicCeliac Diseasemedicine.anatomical_structureGastric MucosaChild PreschoolAntibody FormationDuodenumbiology.proteinDuodenal mucosaFemaleHistopathologyAntibodycoeliac disease diagnosis [anti-endomysial antibodies; cultured duodenal mucosa]businessScandinavian Journal of Gastroenterology
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Gluten Induces Subtle Histological Changes in Duodenal Mucosa of Patients with Non-Coeliac Gluten Sensitivity : A Multicentre Study

2022

Background: Histological changes induced by gluten in the duodenal mucosa of patients with non-coeliac gluten sensitivity (NCGS) are poorly defined. \ud \ud \ud \ud Objectives: To evaluate the structural and inflammatory features of NCGS compared to controls and coeliac disease (CeD) with milder enteropathy (Marsh I-II). \ud \ud \ud \ud Methods: Well-oriented biopsies of 262 control cases with normal gastroscopy and histologic findings, 261 CeD, and 175 NCGS biopsies from 9 contributing countries were examined. Villus height (VH, in μm), crypt depth (CrD, in μm), villus-to-crypt ratios (VCR), IELs (intraepithelial lymphocytes/100 enterocytes), and other relevant histological, serologic, and…

Settore MED/12 - GastroenterologiaNutrition and DieteticsSettore MED/09 - Medicina InternaGlutensDuodenumnon-coeliac gluten sensitivityBiopsySettore MED/08 - Anatomia Patologica3121 Internal medicinedigestive systemhistologynormal mucosaCeliac DiseaseDiet Gluten-FreeHumansIntestinal Mucosanon-coeliac gluten sensitivity; histology; normal mucosa; coeliac diseasecoeliac disease; histology; non-coeliac gluten sensitivity; normal mucosacoeliac diseaseFood Science
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Multiple sclerosis-like neurological manifestations in a coeliac patient: nothing is as it seems

2012

Cobalamin (vitamin B12) deficiency occurs with several disorders, involving different organs and systems, including blood, bowel, nervous system and eyes. Although the most important features are usually haematological ones, presence of neurological involvement, in the absence of blood count alterations, has just been described in the literature. Here we report the case of a 48-year-old man, suffering from coeliac disease for approximately 5 years, vegetarian, who was admitted to our department, referring dysaesthesia of the left lower limb, decreased libido and erectile dysfunction. Vitamin B12 deficiency was proved, even in the absence of blood count alteration, and treated with a vitamin…

MaleNervous systemmedicine.medical_specialtyMultiple SclerosisSettore MED/09 - Medicina InternaGastroenterologyCobalaminArticleCoeliac diseaseDiagnosis DifferentialMultiple sclerosis; coeliac diseasechemistry.chemical_compoundFolic AcidErectile DysfunctionInternal medicinemedicineHumansMultiple sclerosiParesthesiaVitamin B12business.industryMultiple sclerosisBrainVitamin B 12 DeficiencyGeneral MedicineMiddle Agedmedicine.diseaseMagnetic Resonance ImagingDecreased LibidoSurgeryCeliac DiseaseErectile dysfunctionmedicine.anatomical_structureSpinal CordchemistryVitamin B ComplexDifferential diagnosisbusinesscoeliac disease
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Oral pathology in untreated coeliac disease

2007

Settore MED/09 - Medicina InternaOral pathology; untreated coeliac diseaseOral pathologyuntreated coeliac disease
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Whole-brain histogram and voxel-based analyses of apparent diffusion coefficient and magnetization transfer ratio in celiac disease, epilepsy, and ce…

2007

BACKGROUND AND PURPOSE: Diffusion and magnetization transfer (MT) techniques have been applied to the investigation with MR of epilepsy and have revealed changes in patients with or without abnormalities on MR imaging. We hypothesized that also in the coeliac disease (CD), epilepsy and cerebral calcifications (CEC) syndrome diffusion and MT techniques could reveal brain abnormalities undetected by MR imaging and tentatively correlated to epilepsy. MATERIALS AND METHODS: Diffusion and MT weighted images were obtained in 10 patients with CEC, 8 patients with CD without epilepsy and 17 healthy volunteers. The whole brain apparent diffusion coefficient (ADC) and MT ratio (MTR) maps were analyze…

Settore MED/26 - NeurologiaMT epilepsy coeliac disease calcifications
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Treatment of giardiasis reverses active coeliac disease to latent celiac disease

2001

Settore MED/09 - Medicina InternaLatent celiac diseaseGiardiasiActive coeliac disease
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Guidelines of the Italian societies of gastroenterology on the diagnosis and management of coeliac disease and dermatitis herpetiformis

2022

Introduction: Coeliac disease and dermatitis herpetiformis are immune-mediated diseases triggered by the consumption of gluten in genetically predisposed individuals. These guidelines were developed to provide general practitioners, paediatricians, gastroenterologists, and other clinicians with an overview on the diagnosis, management and follow-up of coeliac patients and those with dermatitis herpetiformis.Methods: Guidelines were developed by the Italian Societies of Gastroenterology. Following a systematic literature review, the Grading of Recommendations Assessment, Development and Evaluation methodol-ogy was used to assess the certainty of the evidence. Statements and recommendations w…

AdultCoeliac disease diagnosiCoeliac disease managementSettore MED/09 - Medicina InternaGlutensHepatologyCoeliac disease diagnosis; Coeliac disease follow-up; Coeliac disease management; Dermatitis herpetiformisGastroenterologyCoeliac disease diagnosisCeliac DiseaseDiet Gluten-FreeHumansDermatitis herpetiformis.Dermatitis herpetiformisChildCoeliac disease follow-upSystematic Reviews as TopicDigestive and Liver Disease
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